For me, this argument is one of the strongest against belief in any gods. Gods are agents. They think, reason, plan, remember, and experience emotions just as humans do. The argument here is that neural science has shown virtually every cognitive ability to be rooted in the functioning of a physical brain. It is extremely unlikely that a mind could exist independently of its physical substrate. The mind evolves as the brain develops from infancy thru adulthood. Its ability to function depends completely on the health of the brain during the life of the organism. It ceases to exist when the brain dies. Gods do not have physical brains. Therefore, gods probably do not exist.
One further note to add here--why thinking behavior (and brains) evolved in animals. Animals, as opposed to most plants, move around in a territory. They compete with each other for resources. They need a sophisticated guidance system, and they need to be able to manipulate objects in their environments. In other words, brains are needed to operate bodies that move. The human mind is certainly the most sophisticated guidance and danger-avoidance system that we know of. It does not seem reasonable to believe that there would be bodiless, brainless beings that would evolve the same kind of goal-directed behavior. That is, human characteristics are a product of a long chain of evolutionary development that meet the survival needs of life forms on a planetary surface. There is no reason why a thinking being should exist without a body to nurture and protect.